With a substantial proportion of the European population having had COVID-19 at some point in the previous years, long-term complications are becoming increasingly prevalent. Studies suggest that about one out of ten people do not fully recover from their acute disease, and present ongoing symptoms for three months or longer. In summer 2022, the EHDEN Evidence Generation Fund … Read more
In September 2022, Frontiers in Big Data published the paper “A concentric circles view of health data relations facilitates understanding of sociotechnical challenges for learning health systems and the role of federated data networks”. While this title may sound daunting, the concept is designed to break down complex health data principles that are important for … Read more
Key Findings To our knowledge this is the largest COVID-19 study to date with more than twenty-four million COVID-19 patients and twenty-six databases across three continents. This study provides essential context on the complications in unvaccinated subjects and shows a striking increase in risk of outcomes after COVID-19, like pulmonary embolism (x12), disseminated intravascular coagulation … Read more
Right now, we are all riding on the Gartner Hype Cycle with regards to ‘AI bots’ and generative pre-trained transformers, based on large language models, such as OpenAI’s ChatGPT 3, or Google’s Bard, based on its LaMDA technology. Despite the excitement, or even hysteria around developments in generative AI (artificial intelligence, but perhaps more EI, … Read more
Dr Ravinder Claire outlines recent progress towards greater use of real-world evidence in regulatory decision-making. He also considers the implications and opportunities for NICE and our stakeholders. This blog entry was previously published by NICE on 24th January 2023 (here). Real-world evidence has the potential to transform current models of evidence generation. It allows … Read more
The use of health data has had an interesting evolution. When I look back to the mid-1980s when I was in general practice in London, and first became aware of the important role computers can play in clinical care, there was initially a lot of resistance, negativity, and fierce debate about the ethics of sharing … Read more
Before I share details about GetReal, let me first outline our evolution. The GetReal Institute was established as an independent and sustainable continuation of two Innovative Medicines Initiative (IMI) projects. IMI GetReal ran between 2013 and 2017 with a focus on bringing together stakeholder groups to develop new tools and resources for incorporating real world … Read more
The OHDSI Europe Symposium 2022 (24-26 June) kicked off aboard the majestic transatlantic ship: the SS Rotterdam (moored permanently on the Meuse river in Rotterdam). It was a very anticipated and successful event in many respects, so I thought it would be worthwhile to reflect on what made this one so special. This was actually … Read more
[This blog post is reproduced with permission of NICE from the original here] The course is made up of six learning modules and can be found on the EHDEN Academy website. The EHDEN Academy is a free learning resource, focusing on providing the knowledge, skills, and tools to access and use real-world evidence. Innovative medical technologies … Read more
My team and I are very pleased to see the COVID-19 virus waning thanks to vaccines (and mutations), and that we’re now in a much better place. However, it’s nevertheless still with us and there’s necessarily great interest in the long-term consequences of long COVID, i.e., infection/re-infection, infection with different variants, infection with people vaccinated, … Read more